Prostate enlargement treatment

Prostate enlargement is caused by an increase in the number of both epithelial and stromal cells. Clinically, prostate enlargement leads to voiding problems, which is most often referred to as lower urinary tract symptoms (LUTS).

Prostate enlargement progression
Prostate enlargement usually occurs in males 45-50 old and progressively involves 75% of the male population over 75 years of age.

Prostate Power Rx - Physician Formulas
Formulated by
Ray-Sahelian, M.D.

 

With Saw Palmetto, Pygeum, Stinging Nettle, Gensitein, Quercetin, Phytoestrogens, and several Ingredients for support of normal prostate health and size.

Prostate Power Rx is carefully formulated with important herbs and nutrients to provide optimal prostate health.
 

Prostate Power Rx Supplement Facts
Saw Palmetto extract
Stinging Nettle extract
Quercetin
Rosemary extract
Beta Sitosterol
Pygeum extract
Daidzein and Genistein (standardized to contain 40% isoflavones)
(treatment with the isoflavones daidzein and genistein, the estrogen-like compounds found in soy, block prostate growth in rats)
Lycopene

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Symptoms of prostate enlargement
Symptoms of prostate enlargement are related primarily to bladder outlet obstructions resulting from enlargement of the prostate gland, and from extrinsic and intrinsic sympathetic activation of alpha-adrenoceptors present in the muscle tissue of the prostate gland, the urethra portion of the prostate gland, bladder base and neck.

  
The symptoms of
prostate enlargement vary, but the most common ones involve changes or problems with urination, such as: A hesitant, interrupted, weak stream; Urgency and leaking or dribbling; More frequent urination, especially at night. This is called nocturia. Men who have symptoms of prostate obstruction are more likely to develop chronic kidney disease.

Prostate enlargement cause
Prostate enlargement may be due to genetics and diet. Hormone changes as we get older also influences the growth of the prostate gland. Prostate gland development requires the conversion of testosterone into DHT with the help of an enzyme called 5-alpha reductase. As aging occurs, the amount of DHT in the prostate gland remains high, even through the circulating testosterone level drops which could lead to prostate enlargement.
   Common NSAID painkillers like ibuprofen and naproxen may increase the risk for prostate enlargement and worsen urinary symptoms in men who already have the condition.

Prostate enlargement treatment
Historically, the only treatments for LUTS due to prostate enlargement were watchful waiting or surgery (transurethral or open prostatectomy). However, over the last three decades, medical treatment has taken a prominent role in the management of prostate enlargement symptoms.
   Several drugs are used in the treatment of a prostate gland.

Medical treatment for prostate enlargement
Current medical treatments for enlarged prostate gland include alpha-adrenergic receptor antagonists, inhibitors of the 5-alpha reductase enzyme and various herbal remedies. Many patients are unable to tolerate the side effects of these medications, or are refractory to medical management and require surgery.

Prostate enlargement Medicines - Prostate enlargement Drugs
Several drugs are currently used for an enlarged prostate gland:

5-alpha reductase inhibitors:
The enzyme 5 alpha-reductase (5 alpha R) catalyses the reduction of testosterone into the more potent androgen dihydrotestosterone. The abnormal production of dihydrotestosterone is associated with pathologies of the main target organs of this hormone: the prostate and the skin. Prostate enlargement, prostate cancer, acne, androgenetic alopecia in men, and hirsutism in women appear related to excess dihydrotestosterone production. Two isozymes of 5 alpha-reductase have been cloned, expressed and characterized (5 alpha R-1 and 5 alpha R-2).

Proscar (finasteride) for enlarged prostate gland, manufactured by Merck. Proscar blocks the conversion of testosterone into the more active dihydrotestosterone.
Fincar - Generic Proscar manufactured by Cipla;
Avodart - Dutasteride manufactured by GlaxoSmithKline;
Dutas - Generic Dutasteride manufactured by Dr. Reddy's.

Alpha 1 blocker for prostate enlargement:
Alpha1-blockers are the medical therapy of choice for symptomatic patients with
prostate enlargement and low risk of clinical progression (e.g. prostate volume < 30-40 ml). Alpha1-blockers have no effect on the long-term risk of acute urinary retention and the risk of surgery. The alpha 1 blocking agents (Terazosin, Doxazosin, Tamsulosin) that improve urinary symptoms.

Flomax - Tamsulosin Hydrochloride manufactured by Boehringer Ingelheim. Terazosin alpha 1 blocker appears to be useful in the treatment of patients with mild- to moderate symptomatic prostate enlargement.

Hormonal treatment of prostate enlargement
LHRH analogs (Leuprorelin and Goserelin) can reduce the testicular production of androgens with reduction in prostate size.

Surgical treatment of prostate enlargement
Many potential new surgical treatment options are available for the treatment of prostate enlargement.

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