Sapindus mukorossi plant and fruit, use in medicine

Sapindus mukorossi fruits and galls contain triterpenoid saponins and dammarane-type saponins. Tirucallane-type triterpenoid saponins from Sapindus mukorossi have anti platelet activity.

As of March 2010, human studies could not be found.

Anti H pylori benefit
Extracts of Sapindus mukorossi inhibit the growth of H. pylori in vitro and, in in vivo studies, the H pylori infection clears within a few days.

Liver protection potential of sapindus mukorossi
Hepatoprotective activity of Sapindus mukorossi and Rheum emodi extracts: In vitro and in vivo studies.
World J Gastroenterol. 2008 April. Ibrahim M, Khaja MN, Aara A, Khan AA, Habeeb MA, Devi YP, Narasu ML, Habibullah CM. Nizam Institute of Pharmacy, Deshmukhi, pochampally (Mandal), Near Ramoji Film City, Nalgonda-508284, Andhra Pradesh, India.
To study the hepatoprotective capacity of Sapindus mukorossi (and Rheum emodi (R. emodi) extracts in CCl(4) treated male rats. The dried powder of Sapindus mukorossi and R. emodi was extracted successively with petroleum ether, benzene, chloroform, and ethanol and concentrated in vacuum. Primary rat hepatocyte monolayer cultures were used for in vitro studies. In vivo, the hepatoprotective capacity of the extract of the fruit pericarp of Sapindus mukorossi and the rhizomes of R. emodi was analyzed in liver injured CCl(4)-treated male rats. The extracts of Sapindus mukorossi and Rheum emodi do have a protective capacity both in vitro on primary hepatocytes cultures and in in vivo in a rat model of CCl(4) mediated liver injury.

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